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Most college football analysts believe the only serious question in the Missouri-Alabama game is the margin by which Alabama will win. Since the Tigers joined the SEC, they haven't been able to compete against the Crimson Tide in their three meetings. Alabama has won the three contests by an average margin of 30 points.
Alabama is coming off a disappointing 2019 season by their standards. The Crimson Tide weren't participants in the college football postseason for the first time since the new playoff system was implemented. Alabama lost their starting quarterback and wide receivers to the NFL draft. However, their returning arsenal includes star running back Najee Harris and wide receiver Jaylen Waddle. Starting quarterback Mac Jones passed for 1,503 yards and 14 touchdowns in limited opportunities last season, including a victory over the Michigan Wolverines in the Citrus Bowl.
Eliah Drinkwitz left Appalachian State to take the head coach position with Missouri. Drinkwitz is keeping everyone in suspense by refusing to name the starting quarterback for the Tigers until game time. Who Drinkwitz names as his starting quarterback may not matter much, as at least 12 Missouri players will miss the opener against Alabama due to COVID-19 concerns.